Evaluation of oxidative stress levels as biomarkers in vitiligo patients
Yükleniyor...
Tarih
2023
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
WOLTERS KLUWER MEDKNOW PUBLICATIONS
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objective: Vitiligo is a skin disease that causes the loss of melanocyte cells, which produce pigment in the skin. There is evidence that oxidative stress plays an important role in vitiligo disease of unknown pathogenesis. Evidence suggests that there is increased oxidative stress in melanocytes in patients with vitiligo. The aim of this study is to investigate oxidative stress markers in patients with vitiligo. Materials and Methods: Blood samples were taken from 23 vitiligo patients and 23 healthy control groups without any disease in Bezmialem Vakif University Hospital Dermatology and Venereal Diseases Outpatient Clinic. Total antioxidant levels (TAS) and total oxidant levels (TOS) were measured photometrically method with blood samples. The oxidative stress index (OSI) was calculated as the TOS to TAS level ratio. Results: When the results of the vitiligo patient group were compared with the control group, TOS and OSI were found to be significantly higher than the control group (P < 0.05). No statistically significant result was found in TAS. Conclusions: Our results show that oxidative stress plays a role in the pathogenesis of vitiligo.
Açıklama
Anahtar Kelimeler
Antioxidant, oxidant, oxidative stress, vitiligo
Kaynak
TURK DERMATOLOJI DERGISI-TURKISH JOURNAL OF DERMATOLOGY
WoS Q Değeri
Q4
Scopus Q Değeri
Q4
Cilt
17
Sayı
4
