Design and Characterization of Polyvinyl Alcohol/Kappa-Carrageenan Pickering Emulsion Biocomposite Films for Potential Wound Care Applications

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dc.authorid0000-0002-1370-7588
dc.authorid0000-0002-0137-8617
dc.authorid0000-0003-2126-0381
dc.authorid0000-0001-7068-2471
dc.contributor.authorYesilyurt, Aysenur
dc.contributor.authorMayakrishnan, Gopiraman
dc.contributor.authorParin, Ugur
dc.contributor.authorKim, Ick Soo
dc.contributor.authorParin, Fatma Nur
dc.contributor.authorUllah, Azeem
dc.date.accessioned2026-02-08T15:14:46Z
dc.date.available2026-02-08T15:14:46Z
dc.date.issued2024
dc.departmentBursa Teknik Üniversitesi
dc.description.abstractThis study aimed to develop polyvinyl alcohol (PVA) and kappa-carrageenan (kappa CA) biocomposite films using a Pickering emulsion technique for wound care applications. Juniper essential oil and modified sepiolite were incorporated to enhance functionality, with films prepared via solvent casting and characterized for structural, thermal, and mechanical properties. The PCOS-2 film exhibited the highest mechanical performance, with Young's modulus of 6.25 +/- 1.3 MPa, tensile strength of 5.65 +/- 1.7 MPa, and elongation at break of 608.96% +/- 72.8%. Antibacterial assays showed inhibition zones of 9 and 10 mm against Staphylococcus aureus and Escherichia coli, respectively, for the PCOS-2 film, while antioxidant activity reached 63% DPPH radical scavenging after 12 h. Additionally, porosity and hydrophilicity were enhanced, as indicated by contact angles of 55 degrees for the control film and 71.2 degrees for PCOS-2. These results underscore the potential of PVA/kappa CA biocomposite films as sustainable and bioactive wound dressings, combining mechanical resilience, bioactivity, and environmental compatibility, with future efforts focused on optimizing antibacterial efficacy against gram-negative bacteria and clinical validation.
dc.identifier.doi10.1002/jbm.a.37850
dc.identifier.issn1549-3296
dc.identifier.issn1552-4965
dc.identifier.issue1
dc.identifier.pmid39719889
dc.identifier.scopus2-s2.0-85212836083
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1002/jbm.a.37850
dc.identifier.urihttps://hdl.handle.net/20.500.12885/5425
dc.identifier.volume113
dc.identifier.wosWOS:001382454000001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofJournal of Biomedical Materials Research Part A
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzWOS_KA_20260207
dc.subjectanti-bacterial efficiency
dc.subjectbiocomposite film
dc.subjectjuniper essential oil
dc.subjectmodified sepiolite
dc.subjectPVA/carrageenan
dc.titleDesign and Characterization of Polyvinyl Alcohol/Kappa-Carrageenan Pickering Emulsion Biocomposite Films for Potential Wound Care Applications
dc.typeArticle

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