PubMed İndeksli Yayınlar Koleksiyonu
Bu koleksiyon için kalıcı URI
Güncel Gönderiler
Öğe An alternative assessment for transit-oriented developments (TODs) with land use/land cover (LULC)(Springer, 2023) Yildirim, Yalcin; Akin, AnilCities experience rapid growth, and various drivers shape this growth. Notably, developing countries experience challenges on land use and transportation conflict. The idea of transit-oriented developments (TODs) is a solution for this concern of urbanization while there is no consensus on defining and identifying them. This study concentrated on the dynamics of land use/land cover (LULC) effects on transit-oriented developments (TODs) by utilizing light rail stations from a metropolitan area in Turkey, as this is the first attempt in this geography. Spatial data covers of high-resolution Sentinel 2A remotely sensed data and Google Earth images acquired in 2021. The study performed the analyses within a 500-m light rail train station buffer. The results reveal that TODs include more urbanized, open space, street connection, commercials, and dense population as expected from the TOD concept. Local officials, practitioners, and developers should be involved with the TOD implementation and policy phases to establish tangible developments in urbanization.Öğe Does play-based experience provide for inclusiveness? A case study of multi-dimensional indicators(Springer, 2022) Yildirim, Yalcin; Keshavarzi, Golnaz; Aman, Amanda R.Playgrounds are not only for play and fun; they are places that offer diverse experiences for all groups of children. Outdoor playgrounds have been studied as an element of public space for their ability to offer an array of amenities and attributes. In addition to design and planning aspects, inclusiveness is a vital attribute of playgrounds. Inclusiveness within playgrounds provides accessibility for all children regardless of age, gender, and ethnicity, as both physical and social access are considered. Given the rapidly changing global agenda affected dramatically by the COVID-19 pandemic and Black Lives Matter movement, playgrounds have gained even more attention and the importance of inclusiveness has become more prevalent. This study examined the inclusiveness of play-based experiences within a playground in San Antonio, Texas, using mixed methods. The study utilized observational methods, behavior mapping, secondary data for spatial mapping, and a survey conducted in order to understand the perception of playground users. This study evaluated the inclusiveness of the playground and analyzed social and physical accessibility relative to the playground by assessing the diversity of users in terms of age, gender, ethnicity, and disability. The findings of this study show that there is a need for additional studies yielding proposed improvements revolving around playground inclusivity. The study results show that urban designers, urban planners, and policymakers need to collaborate in order to create opportunities that work to eliminate social and physical disparities and that ultimately enhance inclusiveness in playgrounds.Öğe Noise complaints, the COVID-19 pandemic, and compact developments: evidence from five American cities(Springer Heidelberg, 2023) Yildirim, Yalcin; Keshavarzi, Golnaz; Arefi, MahyarThe COVID-19 continues to take its toll on human life. Even though to a less threatening extent, and insignificant to some, noise turns out to be one of its consequences without consensus. While individuals experience multiple restrictions and restrain from exuberant activities by spending most of their time at home, reducing public transportation and personal vehicles, overall, they end up reduce anthropogenic noise pressure. On another level, people continue reporting noise concerns at various degrees during the COVID-19 pandemic. To draw a bigger picture as to whether or not these complaints have increased during the COVID-19 compared to the same period last year, this research examines them in five major American cities: New York, Chicago, San Francisco, Phoenix, and Dallas. Furthermore, the study also assessed the complaint patterns, whether reported in compact or sprawled areas. The findings highlight that either the noise complaints increased or decreased during the COVID-19 crisis. Accordingly, four of the five selected cities, except San Francisco, showed a decrease in reported noise. As it turns out, compact developments correlate significantly and positively with noise complaints in all study areas, except in Phoenix. These findings call for regulating and prioritizing noise-related policies. Planners and urban designers can thus advise to sustain environmental planning and public health issues, especially in planning compact developments.Öğe Diffusion Alignment Coefficient (DAC): A Novel Similarity Metric for Protein-Protein Interaction Network(Ieee Computer Soc, 2023) Altuntas, VolkanInteraction networks can be used to predict the functions of unknown proteins using known interactions and proteins with known functions. Many graph theory or diffusion-based methods have been proposed, using the assumption that the topological properties of a protein in a network are related to its biological function. Here we seek to improve function prediction by finding more similar neighbors with a new diffusion-based alignment technique to overcome the topological information loss of the node. In this study, we introduce the Diffusion Alignment Coefficient (DAC) algorithm, which combines diffusion, longest common subsequence, and longest common substring techniques to measure the similarity of two nodes in protein interaction networks. As a proof of concept, our experiments, conducted on a real PPI networks S.cerevisiae and Homo Sapiens, demonstrated that our method obtained better results than competitors for MIPS and MSigDB Collections hallmark gene set functional categories. This is the first study to develop a measure of node function similarity using alignment to consider the positions of nodes in protein-protein interaction networks. According to the experimental results, the use of spatial information belonging to the nodes in the network has a positive effect on the detection of more functionally similar neighboring nodes.Öğe Seeking the Nexus Between Building Acoustics and Urban Form: A Systematic Review(Springer Heidelberg, 2023) Yildirim, Yalcin; Arefi, MahyarPurpose of ReviewNoise is penetrating urban life pervasively and is imperative for demonstrating the factors behind it regarding built environment, aka buildings and urban form. So, this review aims to provide a better understanding of the association between building acoustics and urban form characteristics.Recent FindingsThere is a growing attention for building acoustics, including materials and simulation aspects with various increasing urban form attributes, i.e., the built and natural environment and transportation.Building acoustics is a key aspect of urban life and falls within the interface of various urban form characteristics. While these two main attributes are not sufficiently addressed, they may adversely affect individuals; thus, all the more reason to explore this nexus. This study has evaluated 67 peer-reviewed journal articles after systematically reviewing the triple resources in assessing building acoustics and urban form between 2016 and 2022. This review separates the indoor and outdoor categories within the simulation, theory, building materials, facade, and the built environment sub-categories. The study does not only review the overall scope of present studies but also direct future directions of their associations.Öğe Investigation of psychological factors related to compassion fatigue, burnout, and compassion satisfaction among nurses(Bmc, 2023) Yesil, Asli; Polat, SehrinazBackground While compassion fatigue is evaluated positively in nurses, compassion fatigue and burnout are undesirable from the viewpoint of professionals, service providers, institutions and ultimately society. It is necessary to identify the factors that lead to undesirable results and to reduce their effects. This study aimed to investigate nurses' levels of compassion fatigue, compassion satisfaction, burnout, various psychopathological symptom levels, coping skills, and the relationship between them. Methods This was a descriptive cross-sectional study. The participants were 356 nurses working in tertiary university hospitals in Istanbul (Turkiye). The Healthcare Professional Information Form, ProQOL-IV, Brief Symptom Inventory, and the Coping Orientations to Problems Experienced scale were used to collect data. Descriptive statistics, correlation analyses, and regression models were used to analyze the data. Results According to the findings, low-level burnout, moderate-high compassion satisfaction, and low-moderate compassion fatigue symptoms were detected. Low-level anxiety, depression, somatization, hostility, and negative self-esteem were found. According to the results of regression analysis, mental disengagement and planning coping strategies positively affect the synergy of compassion fatigue (p < 0.05). Turning religion and restraint coping have a positive effect on compassion fatigue (p < 0.05). While depression has a positive effect on burnout, nurses' positive reinterpretation and growth strategy is effective in coping with burnout (p < 0.05). Positive reinterpretation and growth coping strategies are also effective in increasing job satisfaction (p < 0.05). Conclusions Nurses showing somatization symptoms are risk factors for compassion fatigue, and nurses showing depression symptoms are risk factors for burnout, so they should be closely monitored and should be given support. Mental disengagement and planning coping strategies can reduce compassion fatigue, and positive reinterpretation and growth methods can reduce burnout and increase compassion satisfaction. It may be useful to provide counseling and training for nurses to use the right coping methods.Öğe The Mechanical Properties of 3D-Printed Polylactic Acid/Polyethylene Terephthalate Glycol Multi-Material Structures Manufactured by Material Extrusion(Mary Ann Liebert, Inc, 2024) Demir, Emre; Duygun, Inal Kaan; Bedeloglu, AyseThe mechanical properties of polylactic acid (PLA), polyethylene terephthalate glycol (PETG), and PLA/PETG structures manufactured using the multi-material additive manufacturing (MMAM) method were studied in this work. Material extrusion additive manufacturing was used to print PLA/PETG samples with various PLA and PETG layer numbers. By varying the top and bottom layer numbers of two thermoplastics, the effect of layer number on the mechanical properties of 3D-printed structures was investigated. The chemical and thermal characteristics of PLA and PETG were investigated using Fourier transform infrared spectroscopy and differential scanning calorimetry. Tensile and flexural strength of 3D-printed PLA, PETG, and PLA/PETG samples were determined using tensile and three-point bending tests. The fracture surfaces of the samples were evaluated using optical microscopy. The results indicated that multi-material part containing 13 layers of PLA and 3 layers of PETG exhibited the highest ultimate tensile strength (65.4 MPa) and a good flexural strength (91.4 MPa). MMAM was discovered to be a viable way for producing PLA/PETG materials with great mechanical performance.Öğe Health, safety, and environmental failure evaluation by hybridizing fuzzy multi-attribute decision-making methods for maritime scrubber systems(Springer, 2022) Bashan, Veysi; Yucesan, Melih; Demirel, Hakan; Gul, MuhammetMany shipping companies have started using scrubbers in their fleet to eliminate sulfur emissions from ships, per IMO (International Maritime Organization) rules. Before and during the scrubbers' selection, the scrubbers' operational failures have also started to appear and cause serious concerns. In this study, classified scrubber types are explained and open type, closed type, and hybrid scrubber systems are evaluated. To contribute to this gap in the literature, scrubber failures were identified, five experts with different perspectives were consulted, and the most common and critical malfunctions were evaluated with the fuzzy best-worst method (F-BWM) and fuzzy technique for order preference by similarity to an ideal solution (F-TOPSIS). F-BWM was used to determine the importance weights of the risk parameters used in evaluating failures since it provides fewer comparisons among pairwise comparison-based decision-making methods and a more consistent judgment in the evaluation. F-TOPSIS, on the other hand, was used to determine the final priority scores of the scrubber failures, taking into account the risk parameter weights obtained in the first stage. It has been preferred due to its easy to useness and based on its closeness to the ideal solution and applicability to risk and failure analysis problems. Considering all different systems in general, important issues such as collection efficiency, sulfur emission problem, abrasion, leakages, pump failures, heat exchanger failures, air fan sealing failures, sensors and failures in monitoring the whole system have been investigated. Results show that too high axial velocity for separator and flooded separator, too high solids concentration in recirculation liquid (SF2), piping leakages (SF5), poor quality or inappropriate consumables and chemicals (SF11), and feed circulation pump problems (SF6) are found to be the most important problems among thirteen failures.Öğe A new approach to enhance quinoa protein nano-aggregates: Combined pH shifting-High pressure homogenization(Elsevier Sci Ltd, 2023) Yildiz, Gulcin; Yildiz, GokcenThe physicochemical characteristics of soluble nano-sized quinoa protein isolates prepared by combined pH shifting and high-pressure homogenization were studied. Commercial quinoa protein isolates were exposed to pH shifting at acidic (pH 2-6) or alkaline (pH 8-12) conditions followed by high-pressure homogenization earlier than neutralizing of pH to 7.0. The pH method under pH 12 followed by high-pressure homogenization was found as the most efficient treatment in the reduction of protein aggregate sizes and transparency, improving soluble protein content and surface hydrophobicity. Quinoa protein isolates treated with pH 12 and high-pressure homogenization increased the solubility from 7.85% to 78.97%, creating quinoa protein isolate nano -aggregates with an average size around 54 nm. The quinoa isolate aggregates were used to produce oil-in-water nanoemulsions, which demonstrated the good stability for 14 d at 4 degrees C. This new approach might present an effective technique for the modification of functional features of quinoa protein isolates.Öğe Health risk assessment of metal(loid)s for land application of domestic sewage sludge in city of Bursa, Turkiye(Springer, 2023) Yakamercan, Elif; Aygun, AhmetThis study aims to determine the potential health risks (Carcinogenic and non-carcinogenic) of metal(loid)s in sewage sludge samples for agricultural purposes. For this purpose, sewage sludge was collected annually from a domestic wastewater treatment plant, and metal(loid)s were determined by ICP-MS. Metal(loid)s concentration in sludge samples was within the legal standards. No statically significant seasonal variation of metal(loid)s were observed. The total cancer risk and the hazard index (HI) of metal(loid)s through ingestion, dermal, and inhalation exposure from sewage sludge samples were estimated. The main risk contributor to metal(loid)s were Pb, Zn, and Ni. The average HI values were 0.75 (child) and 0.09 (adult). The total carcinogenic risk (TCR) for child and adult was found to be 3.43 x 10(-5) and 2.31 x 10(-5), respectively. EPA risk assessment model and Monte Carlo Simulation were used to estimate probability and sensitivity distributions for carcinogenic and non-carcinogenic risks. Sensitivity analysis showed that metal(loid)s concentration, exposure duration, exposure frequency, and body weight significantly affect total health risk. The sewage sludge can be applied safely in agriculture due to no important carcinogenic and non-carcinogenic risk for child and adult.Öğe Comprehensive understanding of electrochemical treatment systems combined with biological processes for wastewater remediation(Elsevier Sci Ltd, 2023) Yakamercan, Elif; Bhatt, Pankaj; Aygun, Ahmet; Adesope, Adedolapo W.; Simsek, HalisThe presence of toxic pollutants in wastewater discharge can affect the environment negatively due to presence of the organic and inorganic contaminants. The application of the electrochemical process in wastewater treatment is promising, specifically in treating these harmful pollutants from the aquatic environment. This review focused on recent applications of the electrochemical process for the remediation of such harmful pol-lutants from aquatic environments. Furthermore, the process conditions that affect the electrochemical process performance are evaluated, and the appropriate treatment processes are suggested according to the presence of organic and inorganic contaminants. Electrocoagulation, electrooxidation, and electro-Fenton applications in wastewater have shown effective performance with high removal rates. The disadvantages of these processes are the formation of toxic intermediate metabolites, high energy consumption, and sludge generation. To overcome such disadvantages combined ecotechnologies can be applied in large-scale wastewater pollutants removal. The combination of electrochemical and biological treatment has gained importance, increased removal performance remarkably, and decreased operational costs. The critical discussion with depth information in this review could be beneficial for wastewater treatment plant operators throughout the world.Öğe PVA/Inulin-Based Sustainable Films Reinforced with Pickering Emulsion of Niaouli Essential Oil for Potential Wound Healing Applications(Mdpi, 2023) Parin, Fatma Nur; El-Ghazali, Sofia; Yesilyurt, Aysenur; Parin, Ugur; Ullah, Azeem; Khatri, Muzamil; Kim, Ick SooIn this study, sustainable water-based films were produced via the solvent-casting method. Petroleum-free-based polyvinyl alcohol (PVA) and carbohydrate-based inulin (INL) were used as matrices. Vegetable-waste pumpkin powder was used in the study because of its sustainability and antibacterial properties. Pickering emulsions were prepared using beta-cyclodextrin. The influence of the different ratios of the beta-cyclodextrin/niaouli essential oil (beta-CD/NEO) inclusion complex (such as 1:1, 1:3, and 1:5) on the morphological (SEM), thermal (TGA), physical (FT-IR), wettability (contact angle), and mechanical (tensile test) characteristics of PVA/inulin films were investigated. Moreover, the antibacterial activities against the Gram (-) (Escherichia coli and Pseudomonas aeruginosa) and Gram (+) (Staphylococcus aureus) bacteria of the obtained films were studied. From the morphological analysis, good emulsion stability and porosity were obtained in the Pickering films with the highest oil content, while instability was observed in the Pickering films with the lowest concentration of oil content. Thermal and spectroscopic analysis indicated there was no significant difference between the Pickering emulsion films and neat films. With the addition of Pickering emulsions, the tensile stress values decreased from 7.3 +/- 1.9 MPa to 3.3 +/- 0.2. According to the antibacterial efficiency results, films containing pumpkin powder and Pickering emulsion films containing both pumpkin powder and a ratio of 1:1 (beta-CD/NEO) did not have an antibacterial effect, while Pickering emulsion films with a ratio of (beta-CD/NEO) 1:3 and 1:5 showed an antibacterial effect against Escherichia coli, with a zone diameter of 12 cm and 17 cm, respectively. Among the samples, the films with ratio of (beta-CD/NEO) 1:5 had the highest antioxidant capacity, as assessed by DPPH radical scavenging at 12 h intervals. Further, none of the samples showed any cytotoxic effects the according to LDH and WST-1 cytotoxicity analysis for the NIH3T3 cell line. Ultimately, it is expected that these films are completely bio-based and may be potential candidates for use in wound healing applications.Öğe The Addition of Opuntia ficus-indica Ethanolic Extract to a Skimmed Milk-Based Extender Impacts Ram Sperm Quality(Wiley, 2023) Allai, Larbi; Druart, Xavier; Terzioglu, Pinar; Louanjli, Noureddine; Nasser, Boubker; Ozturk, Mehmet; El Amiri, BouchraRecently, researchers have focused on the use of natural antioxidants to improve semen quality as a key element for successful artificial insemination. In this context, the first aim of this study was to determine the antioxidant activity and composition (minerals, vitamins, and sugars) of Opuntia fcus-indica cladode ethanolic extract (ETHEX). A further purpose of the study was to investigate the effect of ETHEX supplementation on the quality of liquid ram semen extended with skim milk (SM) at 5 degrees C. The antioxidant activity of ETHEX was studied using free radical 1, 1-diphenyl-2-picrylhydrazyl (DPPH center dot) assay. The mineral composition and the sugar and vitamin contents of ETHEX were determined using an inductively coupled plasma optical emission spectrometry (ICP-OES) and HPLC-DAD-RID analytical instruments. As a second part, semen was collected from five Boujaad rams with an artificial vagina. The ejaculates with more than 70% motility were pooled, extended with skim milk (SM) extender without (control) or supplemented with 1-8% of ETHEX (37 degrees C; 0.8 x 109 sperm/mL). Sperm quality parameters were assessed at 8, 24, 48, and 72 h. The results showed that ETHEX had a higher antioxidant activity compared to those of ascorbic acid and butylated hydroxytoluene (BHT). Furthermore, ETHEX contains a considerable amount of minerals, vitamins, and sugars. The inclusion of 1 or 2% ETHEX in SM increased the sperm motility, viability, and membrane integrity and decreased the abnormality of spontaneous and catalyzed lipids peroxidation (p < 0.05) up to 72 h. In addition, semen diluted with 1 and 2% ETHEX decreased the level of DNA fragmentation compared to the control group (p < 0.05). In conclusion, the ETHEX could be recommended to improve the quality of liquid ram spermatozoa. However, its effects on artificial insemination should be further studied.Öğe Cytotoxic and genotoxic effects of leaking chemicals from serum infusion sets: an in-vitro study(Oxford Univ Press, 2023) Ozlu, Aysegul; Taner, GokceSafety concerns about medical devices playing important role in health sciences and bioengineering research are rising day by day. Although there are specific standards regarding disposable medical materials, the information is updating with the toxicological studies. In this study, cytotoxic/genotoxic effects of chemicals leaking from serum infusion sets that have an important place in the clinic were investigated. Media containing leakage chemicals were prepared from equal samples taken from the plastic line sections of 13 different brands of serum infusion sets containing phthalates and the effects on the cultured cells were compared with the untreated control groups. To obtain leaking chemicals, extracting period was selected as 72 h, a routine set-change time in the clinic as indicated in various publications. Neutral red uptake and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide tests were performed in L929 cells to determine cytotoxicity, and cytokinesis blocked micronucleus technique was performed in lymphocytes to determine genotoxicity. Cytotoxic and genotoxic damage levels were compared by evaluating cell-viability rates relative to control, micronucleus frequency, and nuclear division index values. The results showed that all sets caused a decrease in cell viability revealing the effects both on lysosomal and mitochondrial activity and increase in micronucleus frequencies in general. The number of similar studies is extremely limited, and in this study in addition to the short-term effects of using the serum infusion sets, the information about the sample tests to determine the biosecurity of disposable medical materials is given.Öğe Evaluation of the cytotoxic and genotoxic/antigenotoxic effects of resveratrol in human limbal explant cultures(Springer, 2023) Can, Gamze Dereli; Taner, Gokce; Aydemir, Cigdem InciPurpose Resveratrol (RSV) is a natural polyphenol phytoalexin compound and has long been considered to possess antioxidant and anti-inflammatory effects. In order to exploit the protective potential of RSV in anterior segment diseases, we investigated the possible cytotoxic, genotoxic/antigenotoxic effects of human limbal explant cultures to RSV and MMC or H2O2 alone and in combination. Methods A total of 18 limbal explant tissues obtained from three corneal donors were placed on the 12 well tissue culture polystyrene plates and cultured for 14 days. Cell growth from limbal explants was observed by inverted phase contrast microscopy. The cytotoxic effects of RSV was studied by neutral red uptake assay. For the assessment of the genotoxic and antigenotoxic effects, basic alkaline technique of comet assay was performed. Results It was found that the concentrations of RSV up to 100 mu M did not significantly affect the viability of outgrowth cells of limbal explant during 24 h exposure. When compared to negative control, all concentrations of RSV alone caused an increase in DNA strand breakage. Interestingly, 10 mu g/mL MMC alone caused similar tail intensity and tail moment values with RSV alone. On the other hand, RSV treatment in all doses seemed to decrease the DNA damage induced by either H2O2 or MMC. Conclusion RSV is an attractive natural compound for the purpose of oxidative stress reduction in ocular surface and can be utilized as a supplement to promote ocular surface regeneration in vivo.Öğe Enhanced Functionality and Bio-Accessibility of Composite Pomegranate Peel Extract-Enriched Boba Balls(Mdpi, 2022) Dundar, Ayse Neslihan; Uzuner, Kubra; Parlak, Mahmud Ekrem; Sahin, Oya Irmak; Saricaoglu, Furkan Turker; Simsek, SenayBoba balls or pearls have recently gained popularity for beverages or food toppings. Boba balls could be developed into functional foods by the encapsulation of bioactive compounds. In this study, gelatin/sodium alginate composite Boba balls enriched with pomegranate peel extract (PPE) at different concentrations (0, 1, 2, and 3%) were prepared. They were characterized in terms of physical, rheological, textural, morphological, and sensory properties, as well as in vitro digestion, bio-accessibility, and release kinetic of PPE. Adding PPE improved the Boba mix's viscoelasticity and decreased the Boba balls' hardness. The increasing PPE ratio significantly (p < 0.05) increased the antioxidant capacity and total phenolic content. The addition of PPE preserved the spherical shape of the Boba balls, and as the PPE ratio increased, new junction zones were observed in SEM images. The in vitro digestibility of PPE was significantly (p < 0.05) improved by preserving PPE from the mouth and gastric medium, and Boba balls showed the highest release and bio-accessibility in the intestinal medium. Consequently, PPE as a by-product could be successfully used at 2% concentration for enhancing the functionality and bio-accessibility of Boba balls without affecting sensory properties.Öğe Multiple kernel fusion: A novel approach for lake water depth modeling(Academic Press Inc Elsevier Science, 2023) Safari, Mir Jafar Sadegh; Arashloo, Shervin Rahimzadeh; Vaheddoost, BabakMultiple kernel fusion (MKF) refers to the task of combining multiple sources of information in the Hilbert space for improved performance. Very often the combined kernel is formed as a linear composition of multiple base kernels where the combination weights are learned from the data. As the first application of an MKF approach in hydrological modeling, lake water depth as one of the pivot factors in the reservoir analysis is simulated by considering different hydro-meteorological variables. The role of each individual input parameter is initially investigated by applying a kernel regression approach. We then illustrate the utility of an MKF formalism which learns kernel combination of weights to yield an optimal composition for kernel regression. A set of 40-year data collected from 27 groundwater and streamflow stations and 7 meteorological stations for precipitation and evaporation parameters in the vicinity of Lake Urmia are utilized for model development. Both visual and quantitative statistical performance criteria illustrate a superior performance for the MKF approach compared to kernel ridge regression (KRR), the support vector regression (SVR), back propagation neural network (BPNN) and auto regressive (AR) models. More specifically, while each individual input parameter fails to provide an accurate prediction for lake water depth modeling, an optimal combination of all input parameters incorporating the groundwater level, streamflow, precipitation and evaporation via a multiple kernel learning approach enhances the predictive performance of the model accuracy in the multiple scenarios. The promising results (RMSE = 0.098 m; R2 = 0.987; NSE = 0.986) may motivate the application of a MKF approach towards solving alternative and complex hydrological problems.Öğe Enhanced dataset synthesis using conditional generative adversarial networks(Springernature, 2023) Mert, AhmetBiomedical data acquisition, and reaching sufficient samples of participants are difficult and time ans effort consuming processes. On the other hand, the success rates of computer aided diagnosis (CAD) algorithms are sample and feature space depended. In this paper, conditional generative adversarial network (CGAN) based enhanced feature generation is proposed to synthesize large sample datasets having higher class separability. Twenty five percent of five medical datasets are used to train CGAN, and the synthetic datasets with any sample size are evaluated and compared to originals. Thus, new datasets can be generated with the help of the CGAN model and lower sample collection. It helps physicians decreasing sample collection processes, and it increases accuracy rates of the CAD systems using generated enhanced data with enhanced feature vectors. The synthesized datasets are classified using nearest neighbor, radial basis function support vector machine and artificial neural network to analyze the effectiveness of the proposed CGAN model.Öğe Recent progress on the phytotoxic effects of hydrochars and toxicity reduction approaches(Pergamon-Elsevier Science Ltd, 2022) Karatas, Okan; Khataee, Alireza; Kalderis, DimitriosHydrothermal carbonization of wet biomasses has been known to produce added-value materials for a wide range of applications. From catalyst substrates, to biofuels and soil amendments, hydrochars have distinct advantages to offer compared to conventional materials. With respect to the agricultural application of hydrochars, both positive and negative results have been reported. The presence of N, P and K in certain hydrochars is appealing and may contribute to the reduction of chemical fertilizer application. However, regardless of biomass, hydrothermal carbonization results in the production of phytotoxic organic compounds. Additionally, hydro chars from sewage sludge often contain heavy metal concentrations which exceed the regulatory limits set for agricultural use. This review critically discusses the phytotoxic aspects of hydrochar and provides an account of the substances commonly responsible for these. Furthermore, phytotoxicity reduction approaches are proposed and compared with each other, in view of field-scale applications.Öğe Development of PVA-Psyllium Husk Meshes via Emulsion Electrospinning: Preparation, Characterization, and Antibacterial Activity(Mdpi, 2022) Parin, Fatma Nur; Ullah, Azeem; Yesilyurt, Aysenur; Parin, Ugur; Haider, Md Kaiser; Kharaghani, DavoodIn this study, polyvinyl alcohol (PVA) and psyllium husk (PSH)/D-limonene electrospun meshes were produced by emulsion electrospinning for use as substrates to prevent the growth of bacteria. D-limonene and modified microcrystalline cellulose (mMCC) were preferred as antibacterial agents. SEM micrographs showed that PVA-PSH electrospun mesh with a 4% amount of D-limonene has the best average fiber distribution with 298.38 +/- 62.8 nm. Moreover, the fiber morphology disrupts with the addition of 6% D-limonene. FT-IR spectroscopy was used to analyze the chemical structure between matrix-antibacterial agents (mMCC and D-limonene). Although there were some partial physical interactions in the FT-IR spectrum, no chemical reactions were seen between the matrixes and the antibacterial agents. The thermal properties of the meshes were determined using thermal gravimetric analysis (TGA). The thermal stability of the samples increased with the addition of mMCC. Further, the PVA-PSH-mMCC mesh had the highest value of contact angle (81 degrees +/- 4.05). The antibacterial activity of functional meshes against Gram (-) (Escherichia coli, Pseudomonas aeruginosa) and Gram (+) bacteria (Staphylococcus aureus) was specified based on a zone inhibition test. PPMD6 meshes had the highest antibacterial results with 21 mm, 16 mm, and 15 mm against Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa, respectively. While increasing the amount of D-limonene enhanced the antibacterial activity, it significantly decreased the amount of release in cases of excess D-limonene amount. Due to good fiber morphology, the highest D-limonene release value (83.1%) was observed in PPMD4 functional meshes. The developed functional meshes can be utilized as wound dressing material based on our data.
