Characterization of pomegranate peel extract loaded nanophytosomes and the enhancement of bio-accessibility and storage stability
Küçük Resim Yok
Tarih
2023
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier Sci Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Nano-phytosomes are lipid-based nano-carriers and rapidly growing technology for products containing phytochemicals. In this study, pomegranate peel extract (PPE) loaded nanophytosomes (NP) were prepared with phosphatidylcholine (PC) based on thin layer hydration method. The characterization of NP such as entrapment efficiency (EE), particle size, poly-dispersity index (PDI),.-potential and microstructural properties was studied and in vitro bioaccessibility and storage stability of bioactive properties were investigated. The highest EE was determined as 94.99 %, indicating a unique ability as nano-carrier. PPE-loaded NPs showed good characteristics, such as lower PDI values (<0.5), lower particle size (166.70-144.40 nm), and spherical shape of microstructure. All NP complexes showed significant bioaccessibility with TPC, CUPRAC, and ABTS values >50 % in the intestinal medium. The lowest TPC and color difference (.E) during 28 days of storage were found at 4.C, although all NP samples showed better stability at all storage temperatures up to 21 days.
Açıklama
Anahtar Kelimeler
Pomegranate by-products, Nanophytosome, In vitro digestion, Nanoencapsulation
Kaynak
Food Chemistry
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
398
