Cycloartane glycosides from Astragalus plumosus var. krugianus and evaluation of their antioxidant potential

dc.authorid0000-0002-2882-6811en_US
dc.contributor.authorDenizli, Nilufer
dc.contributor.authorHoro, Ibrahim
dc.contributor.authorGulcemal, Derya
dc.contributor.authorMasullo, Milena
dc.contributor.authorFesta, Michela
dc.contributor.authorKoz, Ömer
dc.date.accessioned2021-03-20T20:15:43Z
dc.date.available2021-03-20T20:15:43Z
dc.date.issued2014
dc.departmentBTÜ, Mühendislik ve Doğa Bilimleri Fakültesi, Kimya Bölümüen_US
dc.description.abstractThe methanol extracts of Astragalus plumosus var. krugianus Chamb. & Matthews afforded sixteen cycloartane glycosides among which krugianoside A, was never reported before. All compounds were evaluated for their cytotoxic activity in human skin fibroblast WS1 cells. For compounds exhibiting no significant effect on WS1 viability, the antioxidant potential was examined. Compounds 1 and 8 prevented elevation of ROS induced by t-BOOH, suggesting the potential activity of these compounds to protect fibroblasts from oxidative stress. (C) 2013 Elsevier B.V. All rights reserved.en_US
dc.description.sponsorshipEge University Research FoundationEge Universityen_US
dc.description.sponsorshipThe authors are grateful to the Ege University Research Foundation (2010 Fen 041) for financial support and also grateful to Nihat Sahin and Dr. Serdar Gokhan Senol for the collection and identification of plant material.en_US
dc.identifier.doi10.1016/j.fitote.2013.10.018en_US
dc.identifier.endpage218en_US
dc.identifier.issn0367-326X
dc.identifier.issn1873-6971
dc.identifier.pmid24216051en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage211en_US
dc.identifier.urihttp://doi.org/10.1016/j.fitote.2013.10.018
dc.identifier.urihttps://hdl.handle.net/20.500.12885/1227
dc.identifier.volume92en_US
dc.identifier.wosWOS:000331420300027en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKoz, Ömer
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofFitoterapiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAstragalus plumosus var. krugianusen_US
dc.subjectCycloartane glycosidesen_US
dc.subjectFibroblastsen_US
dc.subjectAntioxidant activityen_US
dc.titleCycloartane glycosides from Astragalus plumosus var. krugianus and evaluation of their antioxidant potentialen_US
dc.typeArticleen_US

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