Cycloartane glycosides from Astragalus plumosus var. krugianus and evaluation of their antioxidant potential
dc.authorid | 0000-0002-2882-6811 | en_US |
dc.contributor.author | Denizli, Nilufer | |
dc.contributor.author | Horo, Ibrahim | |
dc.contributor.author | Gulcemal, Derya | |
dc.contributor.author | Masullo, Milena | |
dc.contributor.author | Festa, Michela | |
dc.contributor.author | Koz, Ömer | |
dc.date.accessioned | 2021-03-20T20:15:43Z | |
dc.date.available | 2021-03-20T20:15:43Z | |
dc.date.issued | 2014 | |
dc.department | BTÜ, Mühendislik ve Doğa Bilimleri Fakültesi, Kimya Bölümü | en_US |
dc.description.abstract | The methanol extracts of Astragalus plumosus var. krugianus Chamb. & Matthews afforded sixteen cycloartane glycosides among which krugianoside A, was never reported before. All compounds were evaluated for their cytotoxic activity in human skin fibroblast WS1 cells. For compounds exhibiting no significant effect on WS1 viability, the antioxidant potential was examined. Compounds 1 and 8 prevented elevation of ROS induced by t-BOOH, suggesting the potential activity of these compounds to protect fibroblasts from oxidative stress. (C) 2013 Elsevier B.V. All rights reserved. | en_US |
dc.description.sponsorship | Ege University Research FoundationEge University | en_US |
dc.description.sponsorship | The authors are grateful to the Ege University Research Foundation (2010 Fen 041) for financial support and also grateful to Nihat Sahin and Dr. Serdar Gokhan Senol for the collection and identification of plant material. | en_US |
dc.identifier.doi | 10.1016/j.fitote.2013.10.018 | en_US |
dc.identifier.endpage | 218 | en_US |
dc.identifier.issn | 0367-326X | |
dc.identifier.issn | 1873-6971 | |
dc.identifier.pmid | 24216051 | en_US |
dc.identifier.scopusquality | Q2 | en_US |
dc.identifier.startpage | 211 | en_US |
dc.identifier.uri | http://doi.org/10.1016/j.fitote.2013.10.018 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12885/1227 | |
dc.identifier.volume | 92 | en_US |
dc.identifier.wos | WOS:000331420300027 | en_US |
dc.identifier.wosquality | Q3 | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.indekslendigikaynak | Scopus | en_US |
dc.indekslendigikaynak | PubMed | en_US |
dc.institutionauthor | Koz, Ömer | |
dc.language.iso | en | en_US |
dc.publisher | Elsevier | en_US |
dc.relation.ispartof | Fitoterapia | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Astragalus plumosus var. krugianus | en_US |
dc.subject | Cycloartane glycosides | en_US |
dc.subject | Fibroblasts | en_US |
dc.subject | Antioxidant activity | en_US |
dc.title | Cycloartane glycosides from Astragalus plumosus var. krugianus and evaluation of their antioxidant potential | en_US |
dc.type | Article | en_US |