Cycloartane glycosides from Astragalus plumosus var. krugianus and evaluation of their antioxidant potential
Küçük Resim Yok
Tarih
2014
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The methanol extracts of Astragalus plumosus var. krugianus Chamb. & Matthews afforded sixteen cycloartane glycosides among which krugianoside A, was never reported before. All compounds were evaluated for their cytotoxic activity in human skin fibroblast WS1 cells. For compounds exhibiting no significant effect on WS1 viability, the antioxidant potential was examined. Compounds 1 and 8 prevented elevation of ROS induced by t-BOOH, suggesting the potential activity of these compounds to protect fibroblasts from oxidative stress. (C) 2013 Elsevier B.V. All rights reserved.
Açıklama
Anahtar Kelimeler
Astragalus plumosus var. krugianus, Cycloartane glycosides, Fibroblasts, Antioxidant activity
Kaynak
Fitoterapia
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
92
