Design and fabrication of auxetic PCL nanofiber membranes for biomedical applications

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dc.authorid0000-0003-2960-5188en_US
dc.contributor.authorBhullar, Sukhwinder Kaur
dc.contributor.authorRana, Deepti
dc.contributor.authorLekesiz, Hüseyin
dc.contributor.authorBedeloğlu, Ayşe
dc.contributor.authorKo, Junghyuk
dc.contributor.authorCho, Yonghyun
dc.date.accessioned2021-03-20T20:13:38Z
dc.date.available2021-03-20T20:13:38Z
dc.date.issued2017
dc.departmentBTÜ, Mühendislik ve Doğa Bilimleri Fakültesi, Makine Mühendisliği Bölümüen_US
dc.description.abstractThe main objective of this study was to fabricate poly (e-caprolactone) (PCL)-based auxetic nanofiber membranes and characterize them for their mechanical and physicochemical properties. As a first step, the PCL nanofibers were fabricated by electrospinning with two different thicknesses of 40 pm (called PCL thin membrane) and 180 pm (called PCL thick membrane). In the second step, they were tailored into auxetic patterns using femtosecond laser cut technique. The physicochemical and mechanical properties of the auxetic nanofiber membranes were studied and compared with the conventional electrospun PCL nanofibers (non-auxetic nano fiber membranes) as a control. The results showed that there were no significant changes observed among them in terms of their chemical functionality and thermal property. However, there was a notable difference observed in the mechanical properties. For instance, the thin auxetic nanofiber membrane showed the magnitude of elongation almost ten times higher than the control, which clearly demonstrates the high flexibility of auxetic nanofiber membranes. This is because that the auxetic nanofiber membranes have lesser rigidity than the control nanofibers under the same load which could be due to the rotational motion of the auxetic structures. The major finding of this study is that the auxetic PCL nanofiber membranes are highly flexible (10-fold higher elongation capacity than the conventional PCL nanofibers) and have tunable mechanical properties. Therefore, the auxetic PCL nanofiber membranes may serve as a potent material in various biomedical applications, in particular, tissue engineering where scaffolds with mechanical cues play a major role.en_US
dc.description.sponsorshipTurkish Scientific and Technical Research Council, TUBITAK, TurkeyTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [214M277]; CSCR, Indiaen_US
dc.description.sponsorshipAuthor acknowledges Turkish Scientific and Technical Research Council, TUBITAK, Turkey for support Project No 214M277 and CSCR, India.en_US
dc.identifier.doi10.1016/j.msec.2017.08.022en_US
dc.identifier.endpage340en_US
dc.identifier.issn0928-4931
dc.identifier.issn1873-0191
dc.identifier.pmid28887981en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage334en_US
dc.identifier.urihttp://doi.org/10.1016/j.msec.2017.08.022
dc.identifier.urihttps://hdl.handle.net/20.500.12885/909
dc.identifier.volume81en_US
dc.identifier.wosWOS:000410253800040en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorBhullar, Sukhwinder Kaur
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofMaterials Science & Engineering C-Materials For Biological Applicationsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectElectrospinningen_US
dc.subjectAuxetic nanofiber membranesen_US
dc.subjectPoly (epsilon-caprolactone)en_US
dc.subjectMechanical behavioren_US
dc.subjectBiomedical applicationsen_US
dc.titleDesign and fabrication of auxetic PCL nanofiber membranes for biomedical applicationsen_US
dc.typeArticleen_US

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