Effect of selenium incorporation on the structure and in vitro bioactivity of 45S5 bioglass

Basit Öğe Kaydı
dc.authorid0000-0003-4114-7044en_US
dc.contributor.authorKarakuzu-lkizler, Burcu
dc.contributor.authorTerzioğlu, Pınar
dc.contributor.authorOduncu-Tekerek, Bilge Sema
dc.contributor.authorYucel, Sevil
dc.date.accessioned2021-03-20T20:09:26Z
dc.date.available2021-03-20T20:09:26Z
dc.date.issued2020
dc.departmentBTÜ, Mühendislik ve Doğa Bilimleri Fakültesi, Polimer Malzeme Mühendisliği Bölümüen_US
dc.description.abstractIn vitro bioactivity, biodegradation, and biocompatibility behavior of a new bioactive glass systems were investigated with the incorporation of selenium oxide, for the replacement of sodium oxide in the traditional 45S5 bioglass composition. The apatite-forming ability of melt-derived bioactive glasses was evaluated by immersion studies in simulated body fluid while monitoring the concentration of silicon, calcium, phosphorus, sodium, and selenium in the medium. The weight loss of bioactive glasses and pH change in the tris-(hydroxymethyl)-amino methane buffer solution was determined to observe the biodegradation behavior of glass samples. The glasses were characterized by a Fourier transform infrared spectroscopy, scanning electron microscopy, inductively coupled plasma, and Vickers hardness measurements. The biocompatibility evaluation of the glasses was determined through in vitro osteogenesis assays by cell viability, alkaline phosphatase activity, and mineralized matrix formation. The incorporation of selenium enhanced the hydroxyapatite formation on the bioactive glass surface and microhardness of glasses. The hardness of glasses was found to decrease with immersion duration. The results indicate that selenium incorporated bioactive glasses can be used as bioactive material in bone tissue engineering applications.en_US
dc.identifier.doi10.1007/s41779-019-00388-6en_US
dc.identifier.endpage709en_US
dc.identifier.issn2510-1560
dc.identifier.issn2510-1579
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage697en_US
dc.identifier.urihttp://doi.org/10.1007/s41779-019-00388-6
dc.identifier.urihttps://hdl.handle.net/20.500.12885/420
dc.identifier.volume56en_US
dc.identifier.wosWOS:000532990000034en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorTerzioğlu, Pınar
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofJournal Of The Australian Ceramic Societyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAlkaline phosphataseen_US
dc.subjectBiodegradationen_US
dc.subjectHydroxyapatiteen_US
dc.subjectMelt-derived bioactive ceramicen_US
dc.subjectSeleniumen_US
dc.titleEffect of selenium incorporation on the structure and in vitro bioactivity of 45S5 bioglassen_US
dc.typeArticleen_US

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WoS İndeksli Yayınlar Koleksiyonu
Polimer Malzeme Mühendisliği Bölümü Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu