Gelatin-Based and Gelatin-Free Electrospun Fibers of Lycopene/Cyclodextrin Inclusion Complexes with Potent Antioxidant Activity

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dc.authorid0000-0001-6220-6504
dc.authorid0000-0002-9011-4495
dc.authorid0000-0002-3989-4481
dc.contributor.authorYildiz, Zehra Irem
dc.contributor.authorTopuz, Fuat
dc.contributor.authorKilic, Mehmet Emin
dc.contributor.authorDurgun, Engin
dc.contributor.authorUyar, Tamer
dc.date.accessioned2026-02-08T15:15:29Z
dc.date.available2026-02-08T15:15:29Z
dc.date.issued2024
dc.departmentBursa Teknik Üniversitesi
dc.description.abstractLycopene, a carotenoid pigment in tomatoes, is used as a dietary supplement with antioxidant effects, but it is vulnerable to environmental factors, such as heat, oxygen, and light. Therefore, there is considerable interest in stabilizing such fragile molecules against environmental influences to preserve their bioactivity during processing and long-term storage. This paper reports the encapsulation and stabilization of lycopene within cyclodextrin (CD) fibers in the presence or absence of gelatin. The successful embedding of lycopene was confirmed by FTIR and NMR analyses. The lycopene's bioactivity could be preserved during processing via electrospinning and long-term storage by stabilizing it against environmental factors. The encapsulated lycopene showed remarkable antioxidant activity, improved thermal stability, and increased UV light stability. The hydrophilic nature of gelatin improved the dissolution of the resulting fibers in water, giving these fibers potential for rapid oral delivery of food-derived molecules encapsulated in fibers.
dc.description.sponsorshipT?rkiye Bilimsel ve Teknolojik Arastirma Kurumu [117Z535]; Scientific and Technological Research Council of Turkey (TUBITAK); TUBITAK-BIDEB [THD-2023-45180]; Istanbul Technical University Research Fund
dc.description.sponsorshipThe Scientific and Technological Research Council of Turkey (TUBITAK, Project No. 117Z535, 2515 COST Program) is acknowledged for funding the research. Z. I. Yildiz thanks TUBITAK-BIDEB for the PhD scholarship. F.T. acknowledges the support received from the Istanbul Technical University Research Fund (under Project number THD-2023-45180).
dc.identifier.doi10.1021/acsfoodscitech.3c00497
dc.identifier.endpage841
dc.identifier.issn2692-1944
dc.identifier.issue4
dc.identifier.scopus2-s2.0-85187987806
dc.identifier.scopusqualityQ2
dc.identifier.startpage833
dc.identifier.urihttps://doi.org/10.1021/acsfoodscitech.3c00497
dc.identifier.urihttps://hdl.handle.net/20.500.12885/5802
dc.identifier.volume4
dc.identifier.wosWOS:001187292600001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherAmer Chemical Soc
dc.relation.ispartofAcs Food Science & Technology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzWOS_KA_20260207
dc.subjectlycopene
dc.subjectcyclodextrin
dc.subjectinclusion-complexation
dc.subjectelectrospinning
dc.subjectantioxidantfibers
dc.titleGelatin-Based and Gelatin-Free Electrospun Fibers of Lycopene/Cyclodextrin Inclusion Complexes with Potent Antioxidant Activity
dc.typeArticle

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