Electrospun Chitosan/Gelatin/Nano-CaCO3 Hybrid Nanofibers for Potential Tissue Engineering Applications

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dc.authorid0000-0003-4114-7044en_US
dc.contributor.authorTerzioğlu, Pınar
dc.date.accessioned2021-03-20T20:09:12Z
dc.date.available2021-03-20T20:09:12Z
dc.date.issued2021
dc.departmentBTÜ, Mühendislik ve Doğa Bilimleri Fakültesi, Polimer Malzeme Mühendisliği Bölümüen_US
dc.description.abstractOrganic-inorganic hybrid materials are promising candidates for biomedical applications. In this study, chitosan, gelatin, and stearic acid coated nano-CaCO3 were electrospun to fabricate non-woven fibrous mats. The prepared chitosan/gelatin/nano-CaCO3 fibers with different CaCO3 contents (0%, 1%, 3%, and 5% w/v to polymer solution) were examined in terms of morphology, structure, thermal behavior, and antibacterial activity. Fourier-transform infrared spectroscopy results confirmed the formation of electrostatic interactions between chitosan, gelatin, and CaCO3. Chitosan/gelatin/nano-CaCO3 could be successfully electrospun into nanofibers with average fiber diameters between 184 +/- 45 and 237 +/- 55 nm and enhanced thermal stability. Electrospinning biopolymer blend with added calcium carbonate at higher concentration (3-5%) resulted in the formation of antibacterial fibers against B. subtilis, C. albicans, K. pneumonia, and S. aureus. According to all these favorable features, electrospun chitosan, gelatin, and nano-CaCO3 fibers seem to be attractive materials for biomedical applications.en_US
dc.identifier.doi10.1080/15440478.2020.1870639en_US
dc.identifier.issn1544-0478
dc.identifier.issn1544-046X
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttp://doi.org/10.1080/15440478.2020.1870639
dc.identifier.urihttps://hdl.handle.net/20.500.12885/297
dc.identifier.wosWOS:000613372800001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorTerzioğlu, Pınar
dc.language.isoenen_US
dc.publisherTaylor & Francis Incen_US
dc.relation.ispartofJournal Of Natural Fibersen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntibacterial activityen_US
dc.subjectelectrospinningen_US
dc.subjectgelatin/chitosan hybridsen_US
dc.subjectpolymer-matrix compositesen_US
dc.subjectstearic acid coated CaCO3en_US
dc.subjectcomposite nanofiberen_US
dc.titleElectrospun Chitosan/Gelatin/Nano-CaCO3 Hybrid Nanofibers for Potential Tissue Engineering Applicationsen_US
dc.typeArticleen_US

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Polimer Malzeme Mühendisliği Bölümü Yayın Koleksiyonu
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