AN OVERVIEW OF THE APPLICATIONS OF NANOMATERIALS AND DEVELOPMENT OF STENTS IN TREATING CARDIOVASCULAR DISORDERS

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dc.contributor.authorBhullar, Sukhwinder Kaur
dc.contributor.authorSingh, Harsharan Pal
dc.contributor.authorKaur, Ginpreet
dc.contributor.authorButtar, Harpal S.
dc.date.accessioned2021-03-20T20:14:50Z
dc.date.available2021-03-20T20:14:50Z
dc.date.issued2016
dc.departmentBTÜ, Mühendislik ve Doğa Bilimleri Fakültesi, Makine Mühendisliği Bölümüen_US
dc.description.abstractThe applications of nanotechnology materials are rapidly advancing and will leave no field untouched by their ground breaking innovations. Nanoparticles are molecules with a diameter ranging from 10-100 nm and are available in different types such as spheres, rods, shells, cages and SERS particles which vary in shape, size and physical properties. The potential applications of nanomaterials include targeted drug and gene delivery, cancer diagnosis and therapy, determination of biological molecules and microorganisms, molecular probes for diagnosis balloon angioplasty, bare metal stents, drug-eluting stents, and bioresorbable stents. Devices manufactured using nanotechnology materials have promising biomedical applications, and most noteworthy among them are the implantable non-woven nanofibrous stents for opening up narrowed blood vessels. The drug-eluting smart stents serve as reservoirs for delivery of medicines that prevent artery closure. The basic characteristics of a well-designed stent are that it must fit snugly in the blocked artery wall and form a scaffold to enhance blood flow without getting dislodged and/or drag-along further in the implanted blood vessel. In addition, the elastic and mechanical behaviour of a stent must match with the native tissue. Nano-robots constitute another important application of nanotechnology in health sciences. These devices may not only help to monitor and record detailed biomechanical and histopathological information of different tissues and organs in both humans and animal models, but also reduce the invasiveness risk and diagnostic cost of human diseases. Due to their specificity and site targeting properties, the nanomaterials may be a real boon for the diagnosis and treatment of diseases. However, several safety and regulatory questions remain to be addressed regarding the usefulness of conventional in vitro and in vivo methods employed for assessing short-and long-term consequences of nanoparticles and nanomaterials in humans, marine and wild animals as well as acute and chronic levels of exposure to environment.en_US
dc.identifier.endpage296en_US
dc.identifier.issn1606-5131
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage286en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12885/1115
dc.identifier.volume44en_US
dc.identifier.wosWOS:000377534900006en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorBhullar, Sukhwinder Kaur
dc.language.isoenen_US
dc.publisherInst Problems Mechanical Engineering-Russian Acad Sciencesen_US
dc.relation.ispartofReviews On Advanced Materials Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[No Keywords]en_US
dc.titleAN OVERVIEW OF THE APPLICATIONS OF NANOMATERIALS AND DEVELOPMENT OF STENTS IN TREATING CARDIOVASCULAR DISORDERSen_US
dc.typeArticleen_US

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