Fabrication of polyamide 6/honey/boric acid mats by electrohydrodynamic processes for wound healing applications

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dc.authorid0000-0003-2048-2951en_US
dc.authorid0000-0002-1370-7588en_US
dc.authorid0000-0003-4114-7044en_US
dc.authorid0000-0001-5340-9609en_US
dc.authorid0000-0002-1640-6035en_US
dc.authorid57407229700en_US
dc.authorscopusid57407773200en_US
dc.authorscopusid57407557400en_US
dc.authorscopusid57407229600en_US
dc.authorscopusid57223309179en_US
dc.contributor.authorTerzioğlu, Pınar
dc.contributor.authorYeşilyurt, Ayşenur
dc.contributor.authorEroğlu, Murat
dc.contributor.authorYıldırım, Kenan
dc.contributor.authorParın, Fatma Nur
dc.contributor.authorParın, Uğur
dc.date.accessioned2022-01-20T07:22:15Z
dc.date.available2022-01-20T07:22:15Z
dc.date.issued2021en_US
dc.departmentBTÜ, Mühendislik ve Doğa Bilimleri Fakültesi, Polimer Malzeme Mühendisliği Bölümüen_US
dc.description.abstractIn this study, polyamide 6, polyamide 6/honey, and polyamide 6/honey/boric acid nanofibrous mats were fabricated by electrospinning and electrospraying technique to be used in wound healing applications. The morphology and diameter of the fiber mats with and without honey and boric acid were examined by scanning electron microscopy. The morphology of fibers showed that all resulting fibers were in the nanometer range with 253–304 nm average fiber diameter. Fourier Transform Infrared spectrum (FT-IR) and thermal gravimetric analysis (TGA) thermograms showed the successful incorporation of honey and boric acid into the fibers. The results demonstrated that increasing the amount of boric acid slightly increased the fiber diameter. Moreover, boric acid incorporation enhanced the hydrophilicity of nanofibers. The wettability and thermal stability of fibers were quite suitable for wound healing applications. Antibacterial tests demonstrated that the polyamide 6/honey fiber was effective against Escherichia coli, while the polyamide 6/honey fibers loaded with boric acid at 5 and 10 wt% concentration were effective against both Escherichia coli and Staphylococcus aureus. However, the fibers had no antibacterial activity against Acinetobacter baumannii and Pseudomonas aeruginosa. The findings showed that polyamide 6/honey and polyamide 6/honey/boric acid nanofibrous scaffolds had desirable characteristics suitable for potential wound healing applicationsen_US
dc.identifier.doi10.1016/j.mtcomm.2021.102921en_US
dc.identifier.doi10.1016/j.mtcomm.2021.102921
dc.identifier.scopusqualityN/Aen_US
dc.identifier.urihttps://hdl.handle.net/20.500.12885/1798
dc.identifier.volume49en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorTerzioğlu, Pınar
dc.institutionauthorYeşilyurt, Ayşenur
dc.institutionauthorEroğlu, Murat
dc.institutionauthorYıldırım, Kenan
dc.institutionauthorParın, Fatma Nur
dc.language.isoenen_US
dc.publisherElsevier Ltden_US
dc.relation.ispartofMaterials Today Communicationsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntibacterial efficiencyen_US
dc.subjectBoric aciden_US
dc.subjectElectrospinningen_US
dc.subjectElectrosprayingen_US
dc.subjectPine honeyen_US
dc.subjectPolyamide-6en_US
dc.titleFabrication of polyamide 6/honey/boric acid mats by electrohydrodynamic processes for wound healing applicationsen_US
dc.typeArticleen_US

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