Artemisinin Yield and Cyto/Genotoxic Properties of Naturally Grown Artemisia Annua L. In Uludag, Turkey

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dc.contributor.authorYaşa, Belkıs
dc.contributor.authorAngın, Naile
dc.contributor.authorErtaş, Murat
dc.contributor.authorTuna, Sibel
dc.contributor.authorÇınar, Aycan
dc.date.accessioned2026-02-08T15:03:28Z
dc.date.available2026-02-08T15:03:28Z
dc.date.issued2022
dc.departmentBursa Teknik Üniversitesi
dc.description200COVID02
dc.description.abstractArtemisia annua L. known as sweet wormwood in ancient literature is an essential oil bearing and medicinal aromatic plant and belongs to Asteraceae family. It has been used for many years in traditional eastern medicine especially in the treatment of malaria and some parasitic diseases, and it gives successful results. Recently, it has been addressed with its potential effect against coronavirus. In this study, naturally growing Artemisia annua L. sample in Uludag, in Bursa province of Turkey, was used as raw drug. The aim of this study is to determine the yields of artemisinin in three different solvent phase extracts using High Performance Liquid Chromatography (HPLC) and examine cytotoxic/genotoxic effect of total ethanol extract on epithelial cells isolated from human bronchial epithelium. The highest amount of artemisinin was found as 0.19 mg/g in ethanol extract. As a result of cell toxicity assay, no cytotoxicity or genotoxicity effect was observed at doses less than 500 µg/mL.
dc.description.sponsorshipThe Scientific Research Project Council of Bursa Technical University
dc.identifier.doi10.38088/jise.1033063
dc.identifier.endpage121
dc.identifier.issn2602-4217
dc.identifier.issue1
dc.identifier.startpage108
dc.identifier.trdizinid517733
dc.identifier.urihttps://doi.org/10.38088/jise.1033063
dc.identifier.urihttps://hdl.handle.net/20.500.12885/4143
dc.identifier.volume6
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherBursa Teknik Üniversitesi
dc.relation.ispartofJournal of Innovative Science and Engineering
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_DergiPark_20260207
dc.subjectEngineering
dc.subjectMühendislik
dc.titleArtemisinin Yield and Cyto/Genotoxic Properties of Naturally Grown Artemisia Annua L. In Uludag, Turkey
dc.typeArticle

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