PVA/WHEY PROTEIN NANOFIBER-COATED PP MELT BLOWN INTEGRATED WITH PICKERING EMULSION OF CITRAL STABILIZED FOR POTENTIAL MEDICAL APPLICATIONS

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dc.contributor.authorParın, Fatma Nur
dc.contributor.authorYesilyurt, Aysenur
dc.contributor.authorParın, Uğur
dc.date.accessioned2026-02-08T15:08:27Z
dc.date.available2026-02-08T15:08:27Z
dc.date.issued2024
dc.departmentBursa Teknik Üniversitesi
dc.description.abstractAs an antibacterial agent with pleasant fragrance, citral (CIT) indicates hydrophobic character, and therefore has low water solubility. In this study, Pickering emulsions were formed and polyvinyl alcohol (PVA)/whey protein hydrophilic nanofibers were coated on PP melt blown non-woven surfaces by electrospinning method. In this context, hydrophobic citral essential oil is stabilized with ?-cyclodextrin (?-CD) in the electrospinning process. PVA and whey protein polymer blend were used as nanofiber matrices. The morphological, physical, and thermal properties of the ?-CD/citral complexes were investigated in PVA/whey protein nanofiber-coated PP non-wovens at various ?-CD levels (1:2, 1:4 and 1:6). Furthermore, zone inhibition procedure was performed to evaluate antibacterial activity of the samples against Gram (+) (Staphylococcus aureus ATCC® 25923) and Gram (-) (Escherichia coli ATCC® 25922, and Pseudomonas aeruginosa ATCC® 27853) bacteria. The morphology of fibers showed that all obtained nanofiber-coated PP surfaces were in the range with 216 - 330 nm average fiber diameter. Fourier Transform Infrared (FT-IR) and thermal gravimetric analysis (TGA) thermograms revealed that citrals were successfully integrated into the bio-based nanofibers. As the amount of citral increased (i.e., the ?-CD/citral increased), the thermal resistance of bio-based nanofiber coated PP surfaces increased. Antibacterial activity indicated the citral-loaded nanofiber-coated PP surfaces were most effective against Escherichia coli, while none of the samples have antibacterial activity against Pseudomonas aeruginosa. Overall, the results displayed that the fabricated PVA/whey protein nanofiber-coated PP samples integrated with Pickering emulsion of citral stabilized have promising wound dressing applications.
dc.identifier.doi10.46460/ijiea.1206901
dc.identifier.endpage7
dc.identifier.issn2587-1943
dc.identifier.issue1
dc.identifier.startpage1
dc.identifier.trdizinid1254302
dc.identifier.urihttps://doi.org/10.46460/ijiea.1206901
dc.identifier.urihttps://hdl.handle.net/20.500.12885/5044
dc.identifier.volume8
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofInternational Journal of Innovative Engineering Applications
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_TR-Dizin_20260207
dc.subjectAntibacterial property
dc.subjectPickering emulsion
dc.subjectPP melt blown
dc.subjectPVA/whey protein nanofiber
dc.subject?-CD/citral complex
dc.titlePVA/WHEY PROTEIN NANOFIBER-COATED PP MELT BLOWN INTEGRATED WITH PICKERING EMULSION OF CITRAL STABILIZED FOR POTENTIAL MEDICAL APPLICATIONS
dc.typeArticle

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