A comparative study of the antibacterial activity of rosemary extract blended with polymeric biomaterials

Basit Öğe Kaydı
dc.contributor.authorBhullar, Sukhwinder Kaur
dc.contributor.authorRana, D.
dc.contributor.authorÖzsel Kaya, Burçak
dc.contributor.authorYadav, R.
dc.contributor.authorKaur, G.
dc.contributor.authorChintamaneni, M.
dc.contributor.authorButtar, H.S.
dc.date.accessioned2021-03-20T20:26:51Z
dc.date.available2021-03-20T20:26:51Z
dc.date.issued2016
dc.departmentBTÜ, Mühendislik ve Doğa Bilimleri Fakültesi, Makine Mühendisliği Bölümüen_US
dc.description.abstractInfection associated with biomaterials is a serious and widespread problem in clinical and translational medicine. Rosemary (Rosmarinus officinalis) is a medicinal herb widely used as an antimicrobial agent. The objective of this study was to investigate the antibacterial activity of rosemary extract blended with synthetic and naturally-derived polymeric biomaterials. Polyvinyl alcohol (PVA) was choosen as a synthetic polymer and chitosan was choosen as a naturally-derived polymer as they are widely used as biomaterials for tissue engineering and drug delivery. The rosemary extract was prepared by maceration extraction method, the polymer membranes were prepared by solvent casting method and the antibacterial activity was done using Gram-negative and Gram-positive strains by pour plate method. The results of this study revealed that the antibacterial activity of rosemary extract increases against both the strains (Gram ?ve and Gram +ve) when blended with synthetic polymer PVA, whereas the activity decreased when combined with PVA-chitosan. It appears that tight binding of chitosan with rosemary extract reduces the antibacterial action of chitosan. Based on this finding, it may be suggested that the rosemary extract may be used as a natural antibacterial agent to treat bactericidal infections associated with the biomaterials. © Copyright 2016 American Scientific Publishers.en_US
dc.identifier.doi10.1166/jbns.2016.1385en_US
dc.identifier.endpage330en_US
dc.identifier.issn1557-7910
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-84990818378en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage326en_US
dc.identifier.urihttp://doi.org/10.1166/jbns.2016.1385
dc.identifier.urihttps://hdl.handle.net/20.500.12885/1293
dc.identifier.volume10en_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorBhullar, Sukhwinder Kaur
dc.language.isoenen_US
dc.publisherAmerican Scientific Publishersen_US
dc.relation.ispartofJournal of Bionanoscienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntibacterial Activityen_US
dc.subjectBiomaterialsen_US
dc.subjectChitosanen_US
dc.subjectPolyvinyl Alcoholen_US
dc.subjectRosmarinus Officinalisen_US
dc.titleA comparative study of the antibacterial activity of rosemary extract blended with polymeric biomaterialsen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu
Makine Mühendisliği Bölümü Yayın Koleksiyonu