A flexible carbon nanofiber and conjugated polymer-based electrode for glucose sensing

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dc.authorid0000-0003-3051-8380
dc.authorid0000-0002-8554-3025
dc.authorid0000-0002-8955-133X
dc.authorid0000-0002-4282-5233
dc.contributor.authorBulut, Umut
dc.contributor.authorSayin, Vuslat Oyku
dc.contributor.authorAltin, Yasin
dc.contributor.authorCevher, Sevki Can
dc.contributor.authorCirpan, Ali
dc.contributor.authorBedeloglu, Ayse Celik
dc.contributor.authorSoylemez, Saniye
dc.date.accessioned2026-02-12T21:05:21Z
dc.date.available2026-02-12T21:05:21Z
dc.date.issued2023
dc.departmentBursa Teknik Üniversitesi
dc.description.abstractHerein, a specific and stable biosensor for glucose using a flexible, modified electrode with a carbon nanofiber (CNF) and a novel conjugated polymer including three moieties of benzotriazole, benzodithiophene, and benzenediamine (P-BDT-BTz:BDA) as a platform was designed. For this purpose, polyacrylonitrile (PAN) nanofiber mats were obtained by a solution-based electrospinning method. PAN nanofiber mats were stabilized and carbonized to turn into carbon nanofibers and the sensing platform was formed by combining the nanofibers on a defined area of a flexible polyethylene terephthalate (PET) substrate. In addition, a random conjugated polymer, P-BDT-BTz:BDA, was synthesized, characterized, and used as a modifier of a CNF-coated transducer surface for glucose detection. The effect of each parameter on biosensor response was evaluated. Under optimized conditions, the electrode responded to glucose in a linear concentration range of 20 mu M to 500 mu M with a detection limit of 8.5 mu M. In addition, it was observed that the designed biosensor has a good sensing ability for glucose in beverages. The results of our study show that the proposed amperometric glucose oxidase (GOx)-based biosensor has high specificity, a low limit of detection, and an extended range of linear detection for glucose.
dc.identifier.doi10.1016/j.microc.2022.108148
dc.identifier.issn0026-265X
dc.identifier.issn1095-9149
dc.identifier.scopus2-s2.0-85142124632
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1016/j.microc.2022.108148
dc.identifier.urihttps://hdl.handle.net/20.500.12885/6921
dc.identifier.volume184
dc.identifier.wosWOS:001004016700001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherElsevier
dc.relation.ispartofMicrochemical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20260212
dc.subjectGlucose detection
dc.subjectCarbon nanofiber
dc.subjectConjugated random polymer
dc.subjectEnzyme immobilization
dc.subjectGlucose oxidase
dc.titleA flexible carbon nanofiber and conjugated polymer-based electrode for glucose sensing
dc.typeArticle

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