Topological and biological assessment of gene networks using miRNA-target gene data

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dc.authorid0000-0003-4469-1440en_US
dc.contributor.authorCingiz, Mustafa Özgür
dc.contributor.authorDiri, B.
dc.date.accessioned2021-03-20T20:26:51Z
dc.date.available2021-03-20T20:26:51Z
dc.date.issued2019
dc.departmentBTÜ, Mühendislik ve Doğa Bilimleri Fakültesi, Bilgisayar Mühendisliği Bölümüen_US
dc.description2019 Innovations in Intelligent Systems and Applications Conference, ASYU 2019 -- 31 October 2019 through 2 November 2019 -- -- 156545en_US
dc.description.abstractIn recent years, different biological data sets obtained by the next generation sequencing techniques have enhanced the analysis of the underlying molecular interactions of diseases. In our study we apply ARNetMiT, C3NET, WGCNA and ARACNE algorithms on microRNA-Target gene datasets to infer gene coexpression networks of breast, prostate, colon and pancreatic cancers. Gene coexpression networks are evaluated according to their topological and biological features. WGCNA based gene coexpression networks fits to scale free network topology more than other gene coexpression networks. In biological assessment there is no obvious difference found between gene coexpression networks which derived from different algorithms. © 2019 IEEE.en_US
dc.identifier.doi10.1109/ASYU48272.2019.8946426en_US
dc.identifier.isbn9781728128689
dc.identifier.scopus2-s2.0-85078345863en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.urihttp://doi.org/10.1109/ASYU48272.2019.8946426
dc.identifier.urihttps://hdl.handle.net/20.500.12885/1292
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorCingiz, Mustafa Özgür
dc.language.isotren_US
dc.publisherInstitute of Electrical and Electronics Engineers Inc.en_US
dc.relation.ispartofProceedings - 2019 Innovations in Intelligent Systems and Applications Conference, ASYU 2019en_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectgene ontology termsen_US
dc.subjectmiRNA-Target genesen_US
dc.subjectgene network inference algorithmsen_US
dc.subjectgene coexpression networksen_US
dc.subjectscale free networksen_US
dc.titleTopological and biological assessment of gene networks using miRNA-target gene dataen_US
dc.title.alternativeMikro RNA-hedef gen verileri kullanilarak elde edilen gen a?larinin topolojik ve biyolojik de?erlendirilmesien_US
dc.typeConference Objecten_US

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