An investigation of PLLA hybrid stent design to overcome thick strut problems

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dc.authorid0000-0003-1500-7347
dc.authorid0000-0002-2947-7510
dc.contributor.authorErdogus, Hakan Burcin
dc.contributor.authorYunus, Doruk Erdem
dc.date.accessioned2026-02-08T15:15:18Z
dc.date.available2026-02-08T15:15:18Z
dc.date.issued2024
dc.departmentBursa Teknik Üniversitesi
dc.description.abstractBiodegradable polymer-based stents simultaneously provide scaffolding, drug release, and biodegradation to eliminate chronic inflammation. The most important factors hindering the wide use of these stents are thick struts, low radial strength, and large footprints formed on the inner wall of the artery as a result of stent expansion. Negative Poisson's Ratio (NPR), also known as the Auxetic design, has shown great potential to provide radial strength with less strut thickness. However, a detailed mechanical evaluation proving improvement in stent performance parameters is not available in the literature. In this study, the performance parameters of two stent designs based on the Auxetic geometry with PLLA were analyzed under in-vivo conditions using an in-silico model consisting of the artery, crimper, and expander FE model. For this purpose, one design utilizes Auxetic unit cell, which is already available in the literature, while the other uses a newly proposed Hybrid design combining Auxetic and Chevron type geometries. Additionally, a specially heated coaxial balloon-catheter system was considered as a deployment tool between glass transition and body temperature, and carried out for thin-strut stent simulations. The Hybrid design is shown to resolve the foreshortening problem of Auxetic design and collapse pressure of commercial PLLA stents. In this present study validates the potential of Hybrid design to overcome problems for polymer-based biodegradable stents.
dc.identifier.doi10.1016/j.ijsolstr.2024.113025
dc.identifier.issn0020-7683
dc.identifier.issn1879-2146
dc.identifier.scopus2-s2.0-85201500884
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1016/j.ijsolstr.2024.113025
dc.identifier.urihttps://hdl.handle.net/20.500.12885/5704
dc.identifier.volume303
dc.identifier.wosWOS:001298021100001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherPergamon-Elsevier Science Ltd
dc.relation.ispartofInternational Journal of Solids and Structures
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzWOS_KA_20260207
dc.subjectStent design
dc.subjectBiodegradable stent
dc.subjectFinite element analysis
dc.subjectForeshortening
dc.subjectCoverage area
dc.titleAn investigation of PLLA hybrid stent design to overcome thick strut problems
dc.typeArticle

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