Synthesis and Molecular Docking Studies of Novel 5-Arylideneaminouracils
Küçük Resim Yok
Tarih
2019
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Maik Nauka/Interperiodica/Springer
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
A series of novel 5-arylideneaminouracils is synthesized from 5-aminouracil and substituted salicylaldehydes, and characterized by spectroscopic methods. DNA interactions of model molecules are explored using molecular docking simulations that reveal that these types of molecules can act as DNA groove binders.
Açıklama
Anahtar Kelimeler
5-aminouracil, Schiff base, molecular docking, DNA binding, groove binder
Kaynak
Russian Journal Of General Chemistry
WoS Q Değeri
Q4
Scopus Q Değeri
Q4
Cilt
89
Sayı
1