Synthesis and Molecular Docking Studies of Novel 5-Arylideneaminouracils

Küçük Resim Yok

Tarih

2019

Yazarlar

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Maik Nauka/Interperiodica/Springer

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

A series of novel 5-arylideneaminouracils is synthesized from 5-aminouracil and substituted salicylaldehydes, and characterized by spectroscopic methods. DNA interactions of model molecules are explored using molecular docking simulations that reveal that these types of molecules can act as DNA groove binders.

Açıklama

Anahtar Kelimeler

5-aminouracil, Schiff base, molecular docking, DNA binding, groove binder

Kaynak

Russian Journal Of General Chemistry

WoS Q Değeri

Q4

Scopus Q Değeri

Q4

Cilt

89

Sayı

1

Künye