Neurotransmitter amino acid adsorption on metal doped boron nitride nanosheets as biosensor: DFT study on neural disease prediagnosis system

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dc.authorid0000-0002-8703-5868
dc.contributor.authorBalkanli, Bugracan
dc.contributor.authorYuksel, Numan
dc.contributor.authorFellah, M. Ferdi
dc.date.accessioned2026-02-08T15:15:29Z
dc.date.available2026-02-08T15:15:29Z
dc.date.issued2024
dc.departmentBursa Teknik Üniversitesi
dc.description.abstractIn this study, pristine and iron (Fe), copper (Cu) and platinum (Pt) metal doped boron nitride nanosheet (BNNS) structures possibility of biosensor, adsorbent and neural disease prediagnosis system for gama amino butyric acid (GABA) and Glutamate (Glu) molecules were investigated by Density Functional Theory (DFT). Metal atoms were doped to replace both boron (B) and nitrogen (N) atoms of BNNS. All the adsorption energies on the structure were calculated as negative values for all structures after the GABA and Glu adsorption. The lowest adsorption energy and enthalpy values reached to - 42.1 kcal/mol and - 42.7 kcal/mol, respectively. According to Gibbs free energy (Delta G) values of adsorption, most of the adsorption reactions can occur spontaneously. The charge transfer during adsorption happened from GABA and Glu molecules to BNNS structures. Based on the results, Fedoped BNNS and Cu-doped BNNS could be utilized as electronic and work function type biosensors for GABA molecule and Glu molecule respectively. This study may lead to future biosensor studies, adsorption studies of neurotransmitter amino acids other than GABA and Glu, and BN nanostructure studies modified with different metal doping.
dc.identifier.doi10.1016/j.sna.2023.114980
dc.identifier.issn0924-4247
dc.identifier.issn1873-3069
dc.identifier.scopus2-s2.0-85183347175
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1016/j.sna.2023.114980
dc.identifier.urihttps://hdl.handle.net/20.500.12885/5787
dc.identifier.volume366
dc.identifier.wosWOS:001152125000001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherElsevier Science Sa
dc.relation.ispartofSensors and Actuators A-Physical
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzWOS_KA_20260207
dc.subjectDFT
dc.subjectBNNS
dc.subjectNeurotransmitter
dc.subjectAdsorption
dc.subjectDetection
dc.subjectBiosensor
dc.titleNeurotransmitter amino acid adsorption on metal doped boron nitride nanosheets as biosensor: DFT study on neural disease prediagnosis system
dc.typeArticle

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