Incorporation of cerium oxide into hydroxyapatite/chitosan composite scaffolds for bone repair

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dc.authorid0000-0002-6685-5656
dc.authorid0000-0003-1324-3741
dc.contributor.authorMutlu, Busra
dc.contributor.authorCaylak, Sena
dc.contributor.authorDuman, Seyma
dc.date.accessioned2026-02-12T21:05:17Z
dc.date.available2026-02-12T21:05:17Z
dc.date.issued2022
dc.departmentBursa Teknik Üniversitesi
dc.description.abstractThis study reports on the production of chitosan-based composite scaffolds reinforced with hydroxyapatite (HA) powders prepared with cerium oxide (CeO2) with various concentrations (10, 20, 30 wt.%). Besides, the effect of CeO2 additive on the microstructural, mechanical and bioactivity properties of the composite scaffolds was investigated. The CeO2 reinforced HA powders were synthesized having homogenous particle distribution via spray drying process. The synthesized powders and the produced scaffolds were examined using different characterization methods. From the results, it can be seen that the scaffolds were significantly affected by amount of CeO2 additive. An increase in the compressive strength is observed as the amount of CeO2 additive rises. Furthermore, the composite scaffolds possessed a high mineralization ability of apatite in simulated body fluid (SBF). These observations related to the composite scaffolds have considerable potency for application in bone tissue engineering.
dc.identifier.doi10.2298/PAC2203207M
dc.identifier.endpage217
dc.identifier.issn1820-6131
dc.identifier.issn2406-1034
dc.identifier.issue3
dc.identifier.scopus2-s2.0-85141315331
dc.identifier.scopusqualityQ3
dc.identifier.startpage207
dc.identifier.urihttps://doi.org/10.2298/PAC2203207M
dc.identifier.urihttps://hdl.handle.net/20.500.12885/6879
dc.identifier.volume16
dc.identifier.wosWOS:000874799500002
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherUniv Novi Sad, Fac Technology
dc.relation.ispartofProcessing and Application of Ceramics
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20260212
dc.subjectcerium oxide
dc.subjecthydroxyapatite
dc.subjectspray drying
dc.subjectmechanical properties
dc.subjectbioactivity properties
dc.titleIncorporation of cerium oxide into hydroxyapatite/chitosan composite scaffolds for bone repair
dc.typeArticle

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