PLA-Based 3D Porous Scaffolds with Bioceramics for Load-Bearing Bone Substitutes

dc.contributor.authorOzer, Hayrunnisa
dc.contributor.authorMutlu, Büşra
dc.contributor.authorDemirci, Fatma
dc.contributor.authorDuman, Seyma
dc.date.accessioned2026-02-08T15:11:03Z
dc.date.available2026-02-08T15:11:03Z
dc.date.issued2025
dc.departmentBursa Teknik Üniversitesi
dc.description.abstractThree-dimensional (3D) printing technology, which has been widely adopted in the field of regenerative medicine, represents a high-speed manufacturing process for biomaterials. Three-dimensional printing technology enables the precise fabrication of biomaterial scaffolds, thereby facilitating the creation of intricate structures that are tailored to the specific characteristics of the defect site. In this study, three-dimensional printing was employed to prepare composite scaffolds comprising poly (lactic acid) and monticellite. The composite scaffolds were optimized through material characterization, mechanical testing, density measurements, and in vitro swelling assessments. The results demonstrated that the Poly (lactic acid)/monticellite composites proposed in this study were highly printable, exhibiting tunable mechanical strength and density in conjunction with the monticellite component. Additionally, the in vitro swelling properties were demonstrated to be superior to those of the neat poly (lactic acid) scaffold. This composite scaffolding of poly (lactic acid) and monticellite represents a promising strategy for load-bearing bone substitutes. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2025.
dc.identifier.doi10.1007/978-3-031-84873-5_23
dc.identifier.endpage291
dc.identifier.issn2730-9576
dc.identifier.scopus2-s2.0-105011524652
dc.identifier.scopusqualityQ4
dc.identifier.startpage279
dc.identifier.urihttps://doi.org/10.1007/978-3-031-84873-5_23
dc.identifier.urihttps://hdl.handle.net/20.500.12885/5207
dc.identifier.volumePart F641
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherSpringer Nature
dc.relation.ispartofSpringer Tracts in Additive Manufacturing
dc.relation.publicationcategoryKitap Bölümü - Uluslararası
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzScopus_KA_20260207
dc.subjectBioceramics
dc.subjectBone tissue engineering
dc.subjectPLA
dc.subjectScaffold
dc.titlePLA-Based 3D Porous Scaffolds with Bioceramics for Load-Bearing Bone Substitutes
dc.typeBook Chapter

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