Impact of nanophase hydroxyapatite-based biomaterials on tissue engineering

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dc.contributor.authorBhullar, Sukhwinder Kaur
dc.contributor.authorGazioğlu Rüzgar, Duygu
dc.contributor.authorSaber-Samandari, S.
dc.contributor.authorSadighi, M.
dc.contributor.authorAhadian, S.
dc.contributor.authorRamalingam, M.
dc.date.accessioned2021-03-20T20:26:56Z
dc.date.available2021-03-20T20:26:56Z
dc.date.issued2018
dc.departmentBTÜ, Mühendislik ve Doğa Bilimleri Fakültesi, Makine Mühendisliği Bölümüen_US
dc.description.abstractBiomaterials are being used over the last few decades as temporary scaffold or permanent implant in tissue engineering, but often encountered with insufficient tissue formation and related functions mainly due to the poor surface interaction of implanted material with host tissues, resulting in failure of the biomaterials. In addition, most of them greatly varied from the tissue to be repaired either chemically or structurally. In this concern, it is essential to design biomaterials with superior surface properties to facilitate favorable host tissue interactions for their long-term survivability and to enhance tissue integeration and regeneration, which typically leads to the concept of nanophase biomaterials. Scaffold plays a critical role in engineering tissues and organs. In designing scaffolds for tissue engineering, in particular engineering bone tissues, researchers have sought not only to create surface active materials but also to mimic composition and structural aspects of bone to promote cell adhesion, cell-matrix interactions, osteointegration, tissue formation, and continued function. Nanophase hydroxyapatite (HA) is a class of ceramic biomaterial that mimics the bone mineral in composition and structure to certain extend and possess unique capabilities for surface interactions with biological entities than conventional HA. It is therefore being considered as a scaffolding system or implant in engineering bone tissues. Keeping these points in view, this article reports the impact of nanophase HA-based biomaterials on bone tissue engineering. © 2018 American Scientific Publishers.en_US
dc.identifier.doi10.1166/jbns.2018.1566en_US
dc.identifier.endpage477en_US
dc.identifier.issn1557-7910
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-85057421389en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage469en_US
dc.identifier.urihttp://doi.org/10.1166/jbns.2018.1566
dc.identifier.urihttps://hdl.handle.net/20.500.12885/1357
dc.identifier.volume12en_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorBhullar, Sukhwinder Kaur
dc.language.isoenen_US
dc.publisherAmerican Scientific Publishersen_US
dc.relation.ispartofJournal of Bionanoscienceen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBiomaterialsen_US
dc.subjectBone Tissue Engineeringen_US
dc.subjectCell-Matrix Interactionsen_US
dc.subjectHydroxyapatiteen_US
dc.subjectNanomaterialsen_US
dc.subjectScaffolden_US
dc.titleImpact of nanophase hydroxyapatite-based biomaterials on tissue engineeringen_US
dc.typeReview Articleen_US

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