Yazar "Tasdelen M.A." seçeneğine göre listele

Listeleniyor 1 - 2 / 2
  • Küçük Resim Yok
    Öğe
    Influence of POSS nanoparticles on the microstructure and mechanical properties of carbon fiber reinforced epoxy hybrid composites
    (John Wiley and Sons Inc, 2021) Kurtulus C.; Kuyumcu M.; Çiftci, Mustafa; Tasdelen M.A.
    The possibility to design composites with superior properties by incorporation of nanoscale reinforcing material still remains to be fulfilled. In the current study, bisphenol A diglycidyl ether-based epoxy resin has been successfully modified with polyhedral oligomeric silsesquioxane (POSS) nanoparticles to give epoxy/POSS nanocomposites. Carbon fiber reinforced composites with different fiber orientations are processed via vacuum bagging technique using this composite as the matrix. Scanning electron microscopy indicated that POSS nanofillers homogeneously distributed in the matrix. As proved by the tensile, flexural, and interlaminar shear strength tests, the inclusion of POSS nanofillers in the polymer matrix has promoted significant improvements in the mechanical properties of the carbon fiber reinforced POSS/epoxy hybrid composites compared to the analogues with neat epoxy matrix. Thus, hybrid composites with exceptional properties are obtained via a straightforward modification in the matrix and a novel paradigm without using any expensive compound has been added to the library of nanocomposite formulations.
  • Küçük Resim Yok
    Öğe
    Synthesis and characterization of bile acid-based polymeric micelle as a drug carrier for doxorubicin
    (John Wiley and Sons Ltd, 2021) Altinkok C.; Acik G.; Karabulut H.R.F.; Çiftci, Mustafa; Tasdelen M.A.; Dag A.
    In the present study, a polymeric micelle based on amphiphilic block copolymer, namely poly(methacrylated methyl lithocholate)-block-poly(oligoethylene glycol methacrylate) (PMML-b-POEGMA) bearing bile acid moiety is prepared via sequential photo-initiated free radical polymerizations, and its drug carrying capacity is investigated using doxorubicin hydrochloride (DOX) as a model drug. For this purpose, two-step procedure is applied in the presence of phenylbis (2,4,6-trimethylbenzoyl)phosphine oxide (BAPO) as bifunctional photo initiator. Based on spectroscopic and chromatographic analyses, the desired amphiphilic block copolymer (PMML-b-POEGMA) is successfully synthesized by wavelength-selective free radical photopolymerization under mild conditions. Finally, the DOX drug is loaded into the PMML-b-POEGMA micelles and then drug release behavior is investigated at two different pH (5.5 and 7.4) values. It is concluded from the results that PMML-b-POEGMA micelles may be used as an efficient nanocarrier to deliver conventional anti-cancer drugs for combination chemotherapy.