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Öğe Development of Silver-Based Bactericidal Composite Nanofibers by Airbrushing(Amer Scientific Publishers, 2018) Bhullar, Sukhwinder Kaur; Rana, Deepti; Özsel Kaya, Burçak; Orhan, Mehmet; Jun, Martin B. G.; Buttar, Harpal S.In this article, we report a simple, cost-effective and eco-friendly method of airbrushing for the fabrication of antibacterial composite nanofibers using Nylon-6 and silver chloride (AgCl). The Nylon-6 is a widely used polymer for various biomedical applications because of its excellent biocompatibility and mechanical properties. Similarly, silver has also been known for their antibacterial, antifungal, antiviral, and anti-inflammatory properties. In order to enhance the antibacterial functionality of the Nylon-6, composite nanofibers in combination with AgCl have been fabricated using airbrush method. The chemical functional groups and morphological studies of the airbrushed Nylon-6/AgCl composite nanofibers were carried out by FTIR and SEM, respectively. The antibacterial activity of airbrushed Nylon-6/AgCl composite nanofibers was evaluated using Gram + ve (Staphylococcus aureus) and Gram -ve (Escherichia coli) bacterial strains. The results showed that the airbrushed Nylon-6/AgCl composite nanofibers have better antibacterial activity against the tested bacterial strains than the airbrushed Nylon-6 nanofibers. Therefore, the airbrushed Nylon-6/AgCl composite nanofibers could be used as a potential antibacterial scaffolding system for tissue engineering and regenerative medicine.Öğe Fabrication and Characterization of Nonwoven Auxetic Polymer Stent(Taylor & Francis Inc, 2015) Bhullar, Sukhwinder Kaur; Ko, Junghyuk; Cho, Yonghyun; Jun, Martin B. G.Synthetic biomaterials have better controlled physical and mechanical properties and can be used to tailor both soft and hard tissues. A tiny, expandable mesh tubes called stents keep blood vessels open and allow blood flow and treat blockage to improve quality of patient's life. The main focus of this work is to (i) fabricate a polymeric sheet of melt electrospun polycaprolactone microfibers; (ii) tailor auxetic geometry by micromachining on polycaprolactone microfiber and polycaprolactone sheet; (iii) fabricate a cylindrical tube to make auxetic stents. Final results for mechanical characterization and performance analysis of auxetic polymer stents are discussed.Öğe Swelling Behavior of Hydrogels within Auxetic Polytetrafluoroethylene Jacket(Taylor & Francis Inc, 2015) Bhullar, Sukhwinder Kaur; Çerkez, İdris; Sezer, Ayşe; Jun, Martin B. G.An acrylamide type hydrogel consisting of 2-acrylamido-2-methyl-1-propanesulfonic acid was synthesized using free radical suspension polymerization. Hydrogel particles were then loaded within an auxetic polytetrafluoroethylene jacket. It was found that the swelling ratio of the hydrogels within the jacket can be controlled by changing the loaded particle's amount and size without the wear and tear of jacket due to the auxetic effect. Increasing swelling ratio with finer hydrogel particles was observed due to higher surface area. On the other hand, increasing hydrogel particle amount resulted in a decrease in water absorption due to diminished free volume for swelling within the jacket.