Teke, Ibrahim T.Ertas, Ahmet H.2026-02-082026-02-0820251526-14921526-1506https://doi.org/10.32604/cmes.2025.066644https://hdl.handle.net/20.500.12885/6022Fatigue failure continues to be a significant challenge in designing structural and mechanical components subjected to repeated and complex loading. While earlier studies mainly examined material properties and how stress affects lifespan, this review offers the first comprehensive, multiscale comparison of strategies that optimize geometry to improve fatigue performance. This includes everything from microscopic features like the shape of graphite nodules to large-scale design elements such as fillets, notches, and overall structural layouts. We analyze and combine various methods, including topology and shape optimization, the ability of additive manufacturing to finetune internal geometries, and reliability-based design approaches. A key new contribution is our proposal of a standard way to evaluate geometry-focused fatigue design, allowing for consistent comparison and encouraging validation across different fields. Furthermore, we highlight important areas for future research, such as incorporating manufacturing flaws, using multiscale models, and integrating machine learning techniques. This work is the first to provide a broad geometric viewpoint in fatigue engineering, laying the groundwork for future design methods that are driven by data and centered on reliability.eninfo:eu-repo/semantics/openAccessFatigue resistancegeometry optimizationtopology optimizationmicrostructural geometryadditive manufacturingcrack initiationmultiaxial fatiguereliability-based designraster orientationnotch effectdefect morphologyfatigue life predictionReview Article10.32604/cmes.2025.0666441441201237WOS:0015309905000012-s2.0-105012097354Q1Q2