Geçim, GözdeDonmez, SinanErkoç, Ertuğrul2021-03-202021-03-2020210272-88421873-3956http://doi.org/10.1016/j.ceramint.2020.09.020https://hdl.handle.net/20.500.12885/306Precipitation of calcium deficient hydroxyapatite nanoparticles in an environmentally benign manner by using only dilute solutions of calcium hydroxide and phosphoric acid without pH adjustment and addition of other chemicals, and water, being the only by-product was investigated by using continuous flow Vortex Reactor (VR) and Semi-Batch Reactor (SBR). The effect of hydrodynamics by changing the Reynolds number of the jets providing residence times of 8.4 ms to 4.37 s for VR, and by changing the stirrer speed between 100 rpm (Re = 2656) and 1000 rpm (Re = 26560) for SBR, on the particle size, particle size distribution, and morphology of the particles was investigated for both systems. It has been shown that it is possible to produce pure phase hydroxyapatite nanoparticles in the desired morphology by changing production system, without resorting to additives. While VR produced rod-like particles with the crystallite size around 4 nm, SBR produced spherical particles with the crystallite size of around 5 nm.eninfo:eu-repo/semantics/closedAccessHydroxyapatiteVortex mixerNanoparticleMixingArticle10.1016/j.ceramint.2020.09.02047219171928WOS:000597776300001Q1Q1