Terzioğlu, Pınar2021-03-202021-03-2020211544-04781544-046Xhttp://doi.org/10.1080/15440478.2020.1870639https://hdl.handle.net/20.500.12885/297Organic-inorganic hybrid materials are promising candidates for biomedical applications. In this study, chitosan, gelatin, and stearic acid coated nano-CaCO3 were electrospun to fabricate non-woven fibrous mats. The prepared chitosan/gelatin/nano-CaCO3 fibers with different CaCO3 contents (0%, 1%, 3%, and 5% w/v to polymer solution) were examined in terms of morphology, structure, thermal behavior, and antibacterial activity. Fourier-transform infrared spectroscopy results confirmed the formation of electrostatic interactions between chitosan, gelatin, and CaCO3. Chitosan/gelatin/nano-CaCO3 could be successfully electrospun into nanofibers with average fiber diameters between 184 +/- 45 and 237 +/- 55 nm and enhanced thermal stability. Electrospinning biopolymer blend with added calcium carbonate at higher concentration (3-5%) resulted in the formation of antibacterial fibers against B. subtilis, C. albicans, K. pneumonia, and S. aureus. According to all these favorable features, electrospun chitosan, gelatin, and nano-CaCO3 fibers seem to be attractive materials for biomedical applications.eninfo:eu-repo/semantics/closedAccessAntibacterial activityelectrospinninggelatin/chitosan hybridspolymer-matrix compositesstearic acid coated CaCO3composite nanofiberArticle10.1080/15440478.2020.1870639WOS:000613372800001Q1Q2